Company Description

DLOC Biosystems is a biotechnology company that is researching organ/tissue on-a-chip technology to provide the most accurate drug development strategies by growing the most inbody mimetic organ models on-chip. It takes $2.6B and 12 years to develop one successful drug because 90% of drugs fail at the late and expensive clinical trial stages. The reason is that preclinical results do not determine the clinical trial failures because tissues grown in the lab do not resemble the tissues in the body. DLOC’s innovative technology has the potential to make drug discovery 50% safer and 40% faster and cheaper. DLOC is achieving this aim by creating patented organ-on-chip devices, automated operating systems, and AI-powered real-time control and data analytics. The devices can grow tissues with microenvironments that resemble in vivo human tissues, where drugs can be tested and their therapeutic index can be better predicted.

Role Description and Key Activities

• Conduct research experiments to model an organ-on-chip for oncology drug testing.
• Carry out standard molecular biology and biochemistry methods with minimal supervision.
• Assist in identifying and characterising experimental models under the guidance of experienced research staff using organ-on-chip devices with minimal supervision.
• Uses laboratory/computer equipment to conduct analyses data of experimental data and present findings to senior staff.
• Present data-supported conclusions in written and oral reports on progress and assist in the development of an intellectual property strategy, including the creation and submission of patent applications.
• Effectively conduct and manage experimental data analysis and interpretation and make appropriate recommendations based on the results.
• In coordination with the company team, perform experimental work following the procedures generated by the R&D team, provide guidance, and supervise the work tasks of less experienced colleagues.
• Work effectively with a multidisciplinary science team to formulate and execute integrated research plans.
• Prepare suitable health & safety documents and ensure they’re in place before work commences.
• Ensure that all company policies and safety practices are followed.
• Work in accordance with the Company Health and Safety Policy, including guidance relating to the use of human tissue (HTA), developing, reviewing, and updating Standard Operating Procedures, COSHH, Safe Systems of Work documents, and risk assessments relevant to their role and in accordance with instruction or training received.
• Maintain and actively pursue continual professional development.

This document outlines the duties required at the current time and indicates the level of
responsibility. It is not a comprehensive or exhaustive list and may vary to include other
reasonable requests.
Essential Qualifications
• Hold a Ph.D. in molecular biology, cancer biology, toxicology, or similar field with preferably
1-5 years relevant industry or research experience in oncology. Ph.D. / Post doctoral
students with relevant experience may be considered.
• Experience in working with mammalian cell culture, preferably using 3D models.
• Experience in working in an environment with laboratory-based research.
• Experience in collaborative working in a relevant environment to achieve team objectives.
• Ability to work using own initiative and to resolve day-to-day issues.
• Excellent organisational skills and the ability to prioritise to deliver high-quality output to
deadlines.
• Clear written and oral communication skills.

Desired but not essential
• Detailed and extensive knowledge of theory and practice related to the areas of skills
relevant to the project (organ-on-chip devices and/or other 3D cell culture models
toxicology studies, PK/PD studies)
• Good knowledge and understanding of GLP standards.

Ability
• Strong results-driven personality.
• Strong commercial awareness and profit-driven motivation.
• High level of enthusiasm, energy, and confidence
• Excellent analytical, communication, organisational and presentation skills
• Work precisely according to procedures, rules and regulations.
• Languages: English, additional languages are a plus

Package
• Up to £45,000 on a full-time basis for the right candidate
• Stock options at the discretion of the Board.

Process and timescales
The closing date for the applications is June 15, 2024. Interviews will be held during the week of June 17.

Please send a CV/resume with a cover letter to – wadah@dlocbiosystems.com

At VIATRIS, we see healthcare not as it is but as it should be. We act courageously and are uniquely positioned to be a source of stability in a world of evolving healthcare needs.

Viatris empowers people worldwide to live healthier at every stage of life.

We do so via:

Access – Providing high quality trusted medicines regardless of geography or circumstance;
Leadership – Advancing sustainable operations and innovative solutions to improve patient health; and
Partnership – Leveraging our collective expertise to connect people to products and services.
Our global portfolio includes best-in-class, iconic brand-name products as well as global key brands; generics, including branded and complex generics; and other offerings across a wide range of therapeutic areas. We are committed to helping create healthier communities worldwide through education, outreach and better access to treatment.

For those driven to live their lives with purpose, Viatris helps employees realise their full potential by creating a collaborative culture that fosters courage and resilience. Viatris is more than just a place to work. This is a place to make a difference in the world.

The Role & What You Will Be Doing

Every day, we rise to the challenge to make a difference and here’s how the Laboratory based Analytical Scientist role will make an impact in the Global Respiratory Group at Viatris where we develop respiratory medicines (e.g., DPIs, MDIs, Nebulised products) for patients worldwide.

Key responsibilities for this role include:

• Working within our Materials Science team, carry out all analytical activities required to deliver new respiratory products to clinical studies and commercialization.
• Plan and execute experiments to develop scientific understanding in the development of analytical methods and during formulation development of new products.
• Perform analyses related to product development, stability and process scale up.
• Process data, interpret results and report experimental outcomes to project development team.
• Highlight aberrant or suspect results and work with a supervisor to investigate.
• Undertake the preparation of protocols, reports and procedures.
• Maintain laboratory documentation in accordance with principles of data integrity and cGMP documentation practices.
• Contribute to project delivery by carrying out other tasks (e.g. laboratory housekeeping, ordering, shipping samples) as required.
• Adherence to all applicable policies and procedures, including those relating to EHS, GMP, GCP, Quality and Compliance, consistent with the role and any associated responsibilities, including people management where applicable.

About Your Skills & Experience

For this role, we’re looking for a candidate who has an effective combination of the following qualifications, skills and experiences:

• Must possess a relevant BSc Degree (for example Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Forensics) or equivalent, or substantial practical work experience.
• Must have a good understanding of the basic principles of physical, organic and analytical chemistry, and be familiar with calculations used in analytical chemistry.
• Must have a good understanding and practical experience of analytical chemistry in product development, including modern laboratory techniques for API, excipient, and drug product testing, e.g., particle sizing, FT-IR, SEM and thermal analysis techniques.
• Must be able to work autonomously to deliver individual tasks; able to organize tasks allocated by supervisor and plan own work to consistently achieve output of high quality results in a timely manner.
• Must be able to work collaboratively within a team environment.
• Must have good understanding of laboratory safety and best practice.
• Must possess good IT skills (Microsoft Excel, Word, and PowerPoint)
• Must possess effective verbal and written communication skills.
• Must have enthusiasm to work in a laboratory based role.

At Viatris, we are dedicated to building a truly diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t fully align with every requirement, we still encourage you to apply. You may just be the right candidate for this or other roles.

Benefits at Viatris

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others. Some of our benefits include the following on top of a competitive salary:

• Top Employer Accreditation, demonstrating that we provide excellent people policies and practices
• Competitive compensation package inclusive of annual discretionary bonus
• Focus on career progression with growth and development opportunities
• Emphasis on Health & Wellness programmes

• 100% paid medical insurance and Employee Assistance Programme
• Life cover
• Excellent employer-matched pension scheme with Viatris contributing up to 11%
• 2 paid volunteer days per year

Diversity & Inclusion at Viatris

At Viatris, diversity and inclusion are essential to our mission. The diversity we foster in all aspects of our business can be one of our greatest strengths in redefining healthcare not as it is, but as it should be. If you would like to know more about what diversity, equity and inclusion means to us, please visit https://www.viatris.com/en/Careers/Diversity-and-Inclusion

Sustainability at Viatris

Corporate social responsibility is fundamental to the Viatris mission. We work to advance responsible and sustainable operations and leverage our collective expertise to empower people to live healthier at every stage of life, recognizing that our actions affect the stakeholders and communities we serve. To learn more about our efforts, please visit https://www.viatris.com/en/about-us/corporate-responsibility

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others.

Viatris is an Equal Opportunity Employer.

Find out more and apply here

At VIATRIS, we see healthcare not as it is but as it should be. We act courageously and are uniquely positioned to be a source of stability in a world of evolving healthcare needs.

Viatris empowers people worldwide to live healthier at every stage of life.

We do so via:

Access – Providing high quality trusted medicines regardless of geography or circumstance;
Leadership – Advancing sustainable operations and innovative solutions to improve patient health; and
Partnership – Leveraging our collective expertise to connect people to products and services.
Our global portfolio includes best-in-class, iconic brand-name products as well as global key brands; generics, including branded and complex generics; and other offerings across a wide range of therapeutic areas. We are committed to helping create healthier communities worldwide through education, outreach and better access to treatment.

For those driven to live their lives with purpose, Viatris helps employees realise their full potential by creating a collaborative culture that fosters courage and resilience. Viatris is more than just a place to work. This is a place to make a difference in the world.

The Role & What You Will Be Doing

As Quality Assurance Officer you will be required to ensure that the Pharmaceutical Quality System is embedded into the MPUK (Viatris) organisation and is efficiently executed, maintained and improved. To provide GMP QA support for global clinical studies, supporting GMP manufacturing, packaging, testing, storage and distribution, and QA support for internal R&D projects. To lead support for studies, projects, Quality initiatives or parts of the Pharmaceutical Quality System. To manage the quality oversight of MPUK external vendors.

Every day, we rise to the challenge to make a difference and here’s how the Quality Assurance Officer role will make an impact:

• To assist in the development and maintenance of specific quality areas/systems within manufacturing, packaging, analytical testing, clinical supply, storage, distribution, and the science and technology development processes.
• To perform manufacturing and packaging batch record reviews, and prepare documentation for batch disposition.
• To assist in the creation, maintenance, review and approval of SOPs as required, ensuring alignment between business lines and MGRG sites, and compliance with current regulations.
• To support the development and maintenance of the training system.
• To support the development and maintenance of documentation controls.
• Manage Quality Investigations, CAPAs, Out of Specification Investigations, Change Controls and complaints, ensuring GMP compliance is maintained.
• To perform internal Quality inspections.
• To represent Quality Assurance in discussions and action plans for assigned clinical studies and R&D projects.
• To manage the oversight of external vendors to support GxP operations. To ensure activities are carried out as required, and that clear roles and responsibilities are defined.
• To lead projects, Quality initiatives or parts of the Pharmaceutical Quality System. This may include multiple business lines within the organisation, and may include other Viatris sites or external vendors.
• To ensure activities are carried out in compliance with Viatris Global policy and regulatory expectations.

About Your Skills & Experience

For this role, we’re looking for a candidate who has an effective combination of the following qualifications, skills and experiences:

• Bachelor’s degree or equivalent/graduate degree preferred in a pharmaceutical (Biology, Chemistry, Pharmacy or related science) and/or technical discipline OR relevant experience (as below).
• To be able to lead projects or Quality initiatives with limited supervision. This may include multiple business lines within the organisation, and may include other Viatris sites or external vendors.
• Demonstrate frontline experience in pharmaceutical drug product QA/QO, OR manufacturing, OR drug product/analytical development.
• Have a clear understanding of the principles and challenges of pharmaceutical GMP.
• Be able to lead technical problems / challenges to clear resolutions.
• Have strong organisational skills, and to be able to work in a structured, logical, articulate, clear and concise manner.
• To be able to work autonomously with limited supervision.
• To have effective verbal and written communication skills, including the ability to work effectively with external vendors, such that Quality oversight can be maintained.

At Viatris, we are dedicated to building a truly diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t fully align with every requirement, we still encourage you to apply. You may just be the right candidate for this or other roles.

Benefits at Viatris

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others. Some of our benefits include the following on top of a competitive salary:

• Top Employer Accreditation, demonstrating that we provide excellent people policies and practices
• Competitive compensation package inclusive of annual discretionary bonus
• Focus on career progression with growth and development opportunities
• Hybrid work model
• Emphasis on Health & Wellness programmes

• 100% paid medical insurance and Employee Assistance Programme
• Life cover
• Excellent employer-matched pension scheme with Viatris contributing up to 11%
• 2 paid volunteer days per year

Diversity & Inclusion at Viatris

At Viatris, diversity and inclusion are essential to our mission. The diversity we foster in all aspects of our business can be one of our greatest strengths in redefining healthcare not as it is, but as it should be. If you would like to know more about what diversity, equity and inclusion means to us, please visit https://www.viatris.com/en/Careers/Diversity-and-Inclusion

Sustainability at Viatris

Corporate social responsibility is fundamental to the Viatris mission. We work to advance responsible and sustainable operations and leverage our collective expertise to empower people to live healthier at every stage of life, recognizing that our actions affect the stakeholders and communities we serve. To learn more about our efforts, please visit https://www.viatris.com/en/about-us/corporate-responsibility

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others.

Viatris is an Equal Opportunity Employer.

Apply here

At VIATRIS, we see healthcare not as it is but as it should be. We act courageously and are uniquely positioned to be a source of stability in a world of evolving healthcare needs.

Viatris empowers people worldwide to live healthier at every stage of life.

We do so via:

Access – Providing high quality trusted medicines regardless of geography or circumstance;
Leadership – Advancing sustainable operations and innovative solutions to improve patient health; and
Partnership – Leveraging our collective expertise to connect people to products and services.
Our global portfolio includes best-in-class, iconic brand-name products as well as global key brands; generics, including branded and complex generics; and other offerings across a wide range of therapeutic areas. We are committed to helping create healthier communities worldwide through education, outreach and better access to treatment.

For those driven to live their lives with purpose, Viatris helps employees realise their full potential by creating a collaborative culture that fosters courage and resilience. Viatris is more than just a place to work. This is a place to make a difference in the world.

The Role & What You Will Be Doing

As Senior Quality Assurance Officer you will be required to ensure that the Pharmaceutical Quality System is embedded into the MPUK (Viatris) organisation and is efficiently executed, maintained and improved. To provide GMP QA support for global clinical studies, supporting GMP manufacturing, packaging, testing, storage and distribution, and QA support for internal R&D projects. To lead support for studies, projects, Quality initiatives or parts of the Pharmaceutical Quality System. To manage the quality oversight of MPUK external vendors.

Every day, we rise to the challenge to make a difference and here’s how the Senior Quality Assurance Officer role will make an impact:

• To assist in the development and maintenance of specific quality areas/systems within manufacturing, packaging, analytical testing, clinical supply, storage, distribution, and the science and technology development processes.
• To perform manufacturing and packaging batch record reviews, and prepare documentation for batch disposition.
• To assist in the creation, maintenance, review and approval of SOPs as required, ensuring alignment between business lines and MGRG sites, and compliance with current regulations.
• To support the development and maintenance of the training system.
• To support the development and maintenance of documentation controls.
• Manage Quality Investigations, CAPAs, Out of Specification Investigations, Change Controls and complaints, ensuring GMP compliance is maintained.
• To perform internal Quality inspections.
• To represent Quality Assurance in discussions and action plans for assigned clinical studies and R&D projects.
• To manage the oversight of external vendors to support GxP operations. To ensure activities are carried out as required, and that clear roles and responsibilities are defined.
• To lead projects, Quality initiatives or parts of the Pharmaceutical Quality System. This may include multiple business lines within the organisation, and may include other Viatris sites or external vendors.
• To ensure activities are carried out in compliance with Viatris Global policy and regulatory expectations.

About Your Skills & Experience

For this role, we’re looking for a candidate who has an effective combination of the following qualifications, skills and experiences:

• Bachelor’s degree or equivalent/graduate degree preferred in a pharmaceutical (Biology, Chemistry, Pharmacy or related science) and/or technical discipline OR relevant experience (as below).
• To be able to lead projects or Quality initiatives with limited supervision. This may include multiple business lines within the organisation, and may include other Viatris sites or external vendors.
• Demonstrate frontline experience in pharmaceutical drug product QA/QO, OR manufacturing, OR drug product/analytical development.
• Have a clear understanding of the principles and challenges of pharmaceutical GMP.
• Be able to lead technical problems / challenges to clear resolutions.
• Have strong organisational skills, and to be able to work in a structured, logical, articulate, clear and concise manner.
• To be able to work autonomously with limited supervision.
• To have effective verbal and written communication skills, including the ability to work effectively with external vendors, such that Quality oversight can be maintained.

At Viatris, we are dedicated to building a truly diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t fully align with every requirement, we still encourage you to apply. You may just be the right candidate for this or other roles.

Benefits at Viatris

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others. Some of our benefits include the following on top of a competitive salary:

• Top Employer Accreditation, demonstrating that we provide excellent people policies and practices
• Competitive compensation package inclusive of annual discretionary bonus
• Focus on career progression with growth and development opportunities
• Hybrid work model
• Emphasis on Health & Wellness programmes

• 100% paid medical insurance and Employee Assistance Programme
• Life cover
• Excellent employer-matched pension scheme with Viatris contributing up to 11%
• 2 paid volunteer days per year

Diversity & Inclusion at Viatris

At Viatris, diversity and inclusion are essential to our mission. The diversity we foster in all aspects of our business can be one of our greatest strengths in redefining healthcare not as it is, but as it should be. If you would like to know more about what diversity, equity and inclusion means to us, please visit https://www.viatris.com/en/Careers/Diversity-and-Inclusion

Sustainability at Viatris

Corporate social responsibility is fundamental to the Viatris mission. We work to advance responsible and sustainable operations and leverage our collective expertise to empower people to live healthier at every stage of life, recognizing that our actions affect the stakeholders and communities we serve. To learn more about our efforts, please visit https://www.viatris.com/en/about-us/corporate-responsibility

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others.

Viatris is an Equal Opportunity Employer.

Apply here

At VIATRIS, we see healthcare not as it is but as it should be. We act courageously and are uniquely positioned to be a source of stability in a world of evolving healthcare needs.

Viatris empowers people worldwide to live healthier at every stage of life.

We do so via:

Access – Providing high quality trusted medicines regardless of geography or circumstance;
Leadership – Advancing sustainable operations and innovative solutions to improve patient health; and
Partnership – Leveraging our collective expertise to connect people to products and services.
Our global portfolio includes best-in-class, iconic brand-name products as well as global key brands; generics, including branded and complex generics; and other offerings across a wide range of therapeutic areas. We are committed to helping create healthier communities worldwide through education, outreach and better access to treatment.

For those driven to live their lives with purpose, Viatris helps employees realise their full potential by creating a collaborative culture that fosters courage and resilience. Viatris is more than just a place to work. This is a place to make a difference in the world.

The Role & What You Will Be Doing

Include introductory paragraph here if available

Every day, we rise to the challenge to make a difference and here’s how the Formulation and Process Scientist role will make an impact:

• Executes experiments to develop the formulation and manufacturing process projects ensuring they meet technical milestones as discussed with supervisor.
• Actively participates in the matrix team to design, and where required, undertake high quality scientific experimentation to further the development of the formulation and manufacturing process of inhaled dosage forms required for project progression.
• Communicates effectively to supervisor and the wider development team and presents data at technical meetings and project team meetings.
• Analyses test data in the context of manufacturing parameters to understand the impact of formulation and processing on product Quality Attributes.
• Operates laboratory scale equipment for inhalation formulation and process development to manufacture products for analytical testing.
• Contributes practical experience to help define the formulation & manufacturing processes in support of pre-clinical, clinical & pivotal regulatory batch manufacture.
• Contributes to authorship of high-quality technical reports on product development activities.
• Adherence to all applicable policies and procedures, including those relating to EHS, GMP, GCP, Quality and Compliance, consistent with the role.
• Perform other duties as assigned consistent with the grade of the role

About Your Skills & Experience

For this role, we’re looking for a candidate who has an effective combination of the following qualifications, skills and experiences:

• Degree OR HND OR equivalent experience in relevant subject (Pharmacy, Pharmaceutical Formulation, Pharmaceutical Sciences, or other related discipline) and relevant pharmaceutical industry experience.
• An understanding of formulation relating to drug product development.
• Experience of formulation or process development in a drug product development role.
• Desire to undertake hands-on laboratory work.
• Familiarity with industrial statistics (ANOVA, regression, Design of Experiments).
• Able to work autonomously to deliver individual tasks; able to organise tasks allocated by supervisor and plan own work to consistently achieve output of high-quality results in a timely manner.
• Proven competence in standard IT systems e.g., Microsoft Windows, Microsoft Office, Internet Browsers.
• Good verbal and written communication skills.
• Be prepared for occasional business travel.

At Viatris, we are dedicated to building a truly diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t fully align with every requirement, we still encourage you to apply. You may just be the right candidate for this or other roles.

Diversity & Inclusion at Viatris

At Viatris, diversity and inclusion are essential to our mission. The diversity we foster in all aspects of our business can be one of our greatest strengths in redefining healthcare not as it is, but as it should be. If you would like to know more about what diversity, equity and inclusion means to us, please visit https://www.viatris.com/en/Careers/Diversity-and-Inclusion

Sustainability at Viatris

Corporate social responsibility is fundamental to the Viatris mission. We work to advance responsible and sustainable operations and leverage our collective expertise to empower people to live healthier at every stage of life, recognizing that our actions affect the stakeholders and communities we serve. To learn more about our efforts, please visit https://www.viatris.com/en/about-us/corporate-responsibility

At Viatris, we offer competitive salaries, benefits and an inclusive environment where you can use your experiences, perspectives and skills to help make an impact on the lives of others.

Viatris is an Equal Opportunity Employer.

Who We Are:
Hume Planning Consultancy Ltd was established in 2001 and focuses on providing independent and creative planning advice to a range of development partners predominantly in London and the South East region. We are a close-knit team of six, with four planners from a range of professional backgrounds.

The Practice prides itself on providing practical, professional input and has a reputation for integrity and long-term relationships with clients. We focus on highlighting the positive benefits of quality development and facilitating investment
with development partners in order to shape attractive, well-functioning places that can be looked back upon with a sense of pride in years to come.

The Opportunity:
As a Graduate Planner, you will be meaningfully engaged in all work streams and an active member of our team. You will be given real challenges and responsibilities to help you develop into a well-rounded planning consultant. With the support of colleagues, you will develop core competencies to help you consolidate your technical skills and confidence as you build your career.

We envisage a start date asap although we would also consider applicants graduating in Summer 2024.

Job Description:

As a part of the Hume Planning team, you will be involved in a diverse range of projects including residential developments, commercial and leisure proposals of varying scales, and will be working alongside members of the team to help deliver these planning proposals on behalf of our client base. The general day-to-day work you can expect to be involved with includes (though is not limited to):

• Review of key planning policy documents and guidance;
• Navigation of LPA planning portals, planning history search, assessment of site context and physical/policy constraints;
• Undertaking of site visits & photos;
• Review of Local Planning Authority (LPA) Local Plans and their stage of production;
• Research for new enquiries and planning appraisals;
• Feedback of research to the team as part of one-to-one or team meetings;
• Cataloguing and progressing new enquiry projects; Preparation of fee proposals to generate new business;
• Contribution to Planning Statements;
• Attendance at various LPA meetings with a member of the team; and
• Attendance at consultation events.

We also expect good time management, organisational skills and assistance with general admin tasks around the office, including answering the phones and taking messages, updating the Hume Planning website.

Your involvement in a broad range of projects will assist you in the completion of your assessment of professional competence (APC) as you work towards becoming a Chartered Member of the Royal Town Planning Institute (RTPI).

Who are we looking for?

We value our team members and are actively seeking a motivated graduate who can join the Practice as we expand in 2024. The successful candidate will demonstrate the following skills:

• a strong drive for results and tangible outcomes;
• a team player with a positive and energetic outlook;
• the desire and ability to adapt to changing situations;
• adept at building relationships with external contacts, including clients and planning officers;
• an ability to plan ahead, and to understand the commercial aspects of the planning process;
• a valid UK driver’s licence;
• a relevant degree; candidates who have completed or in the process of completing an RTPI accredited MSc/MA in a related discipline will be favourably considered.

You should have a passion for planning and creative solutions to development, demonstrated through your studies and/or your extra-curricular activities. The ideal candidate may have demonstrated work experience in a related field. All applicants should be eligible to work in the UK at the time you start employment.

We look forward to hearing from candidates who meet the above criteria.

Interested applicants should contact Alister Hume by email with a covering letter and a copy of your CV (alister.hume@humeplanning.co.uk).

York Bioanalytical Solutions is the premier, independent UK-based provider of bioanalytical, metabolism and ADME services to the world’s pharmaceutical industry. As such, we have strong ideas about the value of our staff in providing a top quality scientific service to our clients and recognise the importance of providing an environment in which our employees feel valued and can develop to the best of their abilities.

Following significant expansion of our DMPK section, we require an experienced scientist to join our friendly, professional team. The successful candidate will play a leading role in the delivery of metabolite characterisation studies in support of human or animal health drug discovery and development, at our facility at Discovery Park in Sandwich, Kent.

The ideal candidate will have:
• In-depth knowledge of metabolite characterisation strategies across drug discovery and development
• Significant expertise in the application of relevant analytical tools to metabolite characterisation studies, including HPLC, radiochemical
detection, UV and mass spectrometry (both nominal mass and high-resolution)
• Detailed understanding of metabolism and enzymology and their significance to drug discovery and drug development programs
• Ability to design and perform iterative metabolism experiments and troubleshoot analytical issues
• Ability to train others to perform all aspects of metabolite characterisation studies
• Flexibility to undertake multiple, potentially complex studies in parallel
• Aptitude for scientific publications, presentations and customer interactions
• A meticulous approach to record keeping and report preparation

Candidates will ideally be educated to degree or higher degree level in a relevant scientific subject. At least 5 years’ experience of work in a metabolite characterisation role is essential. The grading of the role is flexible dependent on experience and relevant qualifications

If you would like to work in a friendly and flexible environment and feel you have the right qualities, please send a detailed CV to:

Angus Nedderman, York Bioanalytical Solutions, Discovery Park House, Discovery Park, Ramsgate Road, Sandwich, Kent, CT13 9ND

angus.nedderman@yorkbio.com; www.yorkbio.com

Company Description
DLOC Biosystems is a biotech contract research organization (CRO) that offers preclinical trials on drugs developed by pharma companies using state-of-the-art organ-on-chip technology. It takes $2.6B and 12 years to develop one successful drug because 90% of drugs fail at the late and expensive clinical trial stages. The reason is that preclinical results do not determine the clinical trial failures because tissues grown in the lab do not resemble the tissues in the body. As a solution, DLOC’s organ-on-chip technology focuses on providing the most accurate drug testing services by growing the most in-body mimetic organ models on-chip.

DLOC’s innovative technology has the potential to make drug discovery 50% safer and 40% faster & cheaper. DLOC is achieving this aim by creating patented organ-on-chip devices, automated operating systems, and AIpowered real-time control & data analytics. The devices can grow tissues with microenvironments that resemble the in vivo human tissues, where drugs can be tested, and their therapeutic index can be better predicted.

Role Description and Key Activities
• Conduct experiments to model an organ-on-chip kidney model to test drug-induced nephrotoxicity.
• Provide day-to-day management of the lab
• Carry out standard molecular biology and biochemistry methods with minimal supervision.
• Assist in identifying and characterizing experimental models under the guidance of experienced research staff using organ-on-chip devices with minimal supervision.
• Analyse data of experimental data collected by themselves.
• Provide guidance and supervise the work tasks of less experienced colleagues.
• Prepare the suitable health & safety documents and ensure they’re in place before work commences.
• Ensure the forward planning and coordination of research technical support in their specialist areas. Discuss requirements with the research technical team & be active in liaison with senior management.
• Work in accordance with HSE guidance relating to the use of human tissue (HTA), developing, reviewing, and updating Standard Operating Procedures, COSHH, Safe Systems of Work documents, and risk assessments relevant to their role and in accordance with instruction or training received.
• Work as a member of a broader Team to fulfill duties commensurate with the post’s grade & nature.
• Maintain and actively pursue continual professional development.

This document outlines the duties required at the current time to indicate the level of responsibility. It is not a comprehensive or exhaustive list and may vary to include other reasonable requests.

Essential Qualifications
• Hold a Ph.D. in molecular biology, toxicology, or relevant field. Equivalent experience is considered.
• Experience in working with cell culture, preferably with kidney models.
• Experience in working in an environment with laboratory-based research
• Experience in collaborative working in a relevant environment to achieve team objectives.
• Ability to work using own initiative and to resolve day-to-day issues.
• Excellent organisational skills and the ability to prioritise to deliver high-quality output to deadlines.
• Clear written and oral communication skills. Experienced in health and safety procedures, including COSHH, and contributing to risk assessments within a life science laboratory environment.

Desired Qualifications
• Detailed and extensive knowledge of theory and practice related to the areas of skills relevant to the project (organ-on-chip devices, cell culture, toxicology studies, nephrology)
• Good knowledge and understanding of GLP standards.

You can apply by sending an email with your CV & cover letter in one PDF to wadah@dlocbiosystems.com