Job Title: Structure Elucidation Senior Scientist at Asymchem
Location: On-site at Discovery Park, Sandwich, Kent
Job Type: Full-time
Company overview
Founded in 1999, Asymchem has grown into a leading global integrated Contract Development and Manufacturing Organization (CDMO), renowned for its innovative solutions and commitment to excellence. Our mission is to drive smarter, greener, and more cost-effective manufacturing to support pharmaceutical and biotech research and commercialization. Our research laboratories and small molecule API pilot plant at Discovery Park, Sandwich, UK, is our flagship site for European R&D and we are looking to recruit into key roles. This is a fantastic opportunity to join an innovative, collaborative, dynamic team of scientists and help shape our operations and the future growth of our organisation.
What we offer
We offer competitive compensation, flexible benefits package including health insurance, retirement plans, opportunities to buy or sell holidays, as well as a good work-life balance. Enjoy a fun and rewarding career with daily opportunities to collaborate with highly talented scientists. Additionally, there will be myriad opportunities to learn new technical and interpersonal skills, develop existing strengths, coach and mentor others, while pursuing our company’s mission.
Position summary
Analytical Research and Development at Asymchem Ltd UK, is seeking an experienced and passionate Structure Elucidation Senior Scientistto join our dynamic, interdisciplinary research team in Sandwich, Kent. Working within our state-of-the-art laboratories, you will play a key role in identifying and characterizing small molecules and complex structures for our development projects.
At Asymchem you will have the opportunity to
- Work both independently and in cross-functional project teams to solve complex analytical and synthetic chemistry problems.
- Work collaboratively with peers to elucidate structures of novel compounds, degradants, impurities and synthetic intermediates using advanced spectroscopic, e.g. NMR (1D, 2D, quantitative), MS (HRMS, MS/MS), and chromatographic techniques.
- Independently design, conduct and interpret advanced NMR experiments (e.g., COSY, HSQC, HMBC, NOESY).
- Demonstrate your comprehensive knowledge and experience of operating, maintaining, and troubleshooting NMR instrumentation and software.
- Demonstrate your experience of operating, maintaining and troubleshooting high-end mass spectrometers and software from different vendors such as Thermo and Agilent.
- Interpret complex spectral data and integrate findings from multiple analytical methods. Provide expert analysis for impurity profiling and degradation product characterization.
- Be highly proficient with structure elucidation software (e.g., MestReNova, ACD/Labs, Bruker TopSpin, MassHunter, FreeStyle).
- Lead authoring of detailed technical reports and a reviewer of reports and data of your peers.
- Interact effectively with team members and partner groups, including verbal presentations, reasoned review of data and preparation of technical reports.
- Effectively communicate progress, plans, requirements and risks to scientists, managers, stakeholders and clients informally and through written reports, emails and presentations.
Qualifications, skills and experience
- Bachelor’s or Master’s degree in Chemistry, Analytical Chemistry, Pharmaceutical Sciences (or a related discipline) with significant relevant industrial experience in area of structure elucidation OR a PhD in Chemistry, Analytical Chemistry, Pharmaceutical Sciences (or a related discipline) with some relevant industrial experience in the field of structure elucidation is essential.
- Excellent troubleshooting skills and ability to develop and implement complex analytical solutions to solve complex chemistry problems is essential.
- A strong desire to develop technical skills and a high learning agility with an ability to apply learning from prior experience to new situations and problems is essential.
- The ability to communicate effectively both in verbal and written forms and to take a collaborative approach to working in a team environment is essential.
- Comfortable working as part of diverse multi-disciplinary, cross-functional teams is essential.
- A good knowledge of small molecule pharmaceutical development and analytical science, with the ability to apply scientific technical skills and knowledge to projects independently and proactively is highly desirable.
- Knowledge in the use of diverse computational, modelling and digital tools is desirable.