EligoChem Limited are pioneering a new drug design technology that enables the discovery of safer drugs.
The EligoChem design technology is based on a recently discovered property of some drugs where by they can display different physical properties in solution and in biological membranes through internalisation of hydrogen bonding and polar surfaces. Drug discovery requires a balance of properties, such that compounds are polar and so soluble enough in water, but also lipophilic and so soluble in oil (body tissues and membranes). Compounds that demonstrate both properties and known as amphiphilic.
The patented technology uses a unique and largely unexplored three-dimensional property that allows compounds to be designed with amphiphilic properties. This technology can be applied to any therapeutic area.