Company Description

DLOC Biosystems is a biotechnology company that is researching organ/tissue on-a-chip technology to provide the most accurate drug development strategies by growing the most inbody mimetic organ models on-chip. It takes $2.6B and 12 years to develop one successful drug because 90% of drugs fail at the late and expensive clinical trial stages. The reason is that preclinical results do not determine the clinical trial failures because tissues grown in the lab do not resemble the tissues in the body. DLOC’s innovative technology has the potential to make drug discovery 50% safer and 40% faster and cheaper. DLOC is achieving this aim by creating patented organ-on-chip devices, automated operating systems, and AI-powered real-time control and data analytics. The devices can grow tissues with microenvironments that resemble in vivo human tissues, where drugs can be tested and their therapeutic index can be better predicted.

Role Description and Key Activities

• Conduct research experiments to model an organ-on-chip for oncology drug testing.
• Carry out standard molecular biology and biochemistry methods with minimal supervision.
• Assist in identifying and characterising experimental models under the guidance of experienced research staff using organ-on-chip devices with minimal supervision.
• Uses laboratory/computer equipment to conduct analyses data of experimental data and present findings to senior staff.
• Present data-supported conclusions in written and oral reports on progress and assist in the development of an intellectual property strategy, including the creation and submission of patent applications.
• Effectively conduct and manage experimental data analysis and interpretation and make appropriate recommendations based on the results.
• In coordination with the company team, perform experimental work following the procedures generated by the R&D team, provide guidance, and supervise the work tasks of less experienced colleagues.
• Work effectively with a multidisciplinary science team to formulate and execute integrated research plans.
• Prepare suitable health & safety documents and ensure they’re in place before work commences.
• Ensure that all company policies and safety practices are followed.
• Work in accordance with the Company Health and Safety Policy, including guidance relating to the use of human tissue (HTA), developing, reviewing, and updating Standard Operating Procedures, COSHH, Safe Systems of Work documents, and risk assessments relevant to their role and in accordance with instruction or training received.
• Maintain and actively pursue continual professional development.

This document outlines the duties required at the current time and indicates the level of
responsibility. It is not a comprehensive or exhaustive list and may vary to include other
reasonable requests.
Essential Qualifications
• Hold a Ph.D. in molecular biology, cancer biology, toxicology, or similar field with preferably
1-5 years relevant industry or research experience in oncology. Ph.D. / Post doctoral
students with relevant experience may be considered.
• Experience in working with mammalian cell culture, preferably using 3D models.
• Experience in working in an environment with laboratory-based research.
• Experience in collaborative working in a relevant environment to achieve team objectives.
• Ability to work using own initiative and to resolve day-to-day issues.
• Excellent organisational skills and the ability to prioritise to deliver high-quality output to
deadlines.
• Clear written and oral communication skills.

Desired but not essential
• Detailed and extensive knowledge of theory and practice related to the areas of skills
relevant to the project (organ-on-chip devices and/or other 3D cell culture models
toxicology studies, PK/PD studies)
• Good knowledge and understanding of GLP standards.

Ability
• Strong results-driven personality.
• Strong commercial awareness and profit-driven motivation.
• High level of enthusiasm, energy, and confidence
• Excellent analytical, communication, organisational and presentation skills
• Work precisely according to procedures, rules and regulations.
• Languages: English, additional languages are a plus

Package
• Up to £45,000 on a full-time basis for the right candidate
• Stock options at the discretion of the Board.

 

Process and timescales
The closing date for the applications is June 15, 2024. Interviews will be held during the week of June 17.

Please send a CV/resume with a cover letter to – wadah@dlocbiosystems.com